Monday, February 2, 2009

Clinical Trials - History

Clinical Trials – History

Clinical Trials is believed to be a practice that concerns to construct human life and is a never ending investigation aimed at finding out the best possible drug to win over the disease of abnormality in a human being. Clinical Trials is not a new term to be heard off. This practice was in existence from times in memory and shall be in practice for times to come. It’s a long journey witnessing success, pains, and transformation.

Clinical Trials history dates back to 605-562 BC….

605-562 BC

Unknowing that this practice of his would be called a clinical trial in future King Nebuchadnezzar II carried out the first ever clinical trial when he ordered that a strict diet of meat and wine be followed for three years by his people. However, four children of royal blood convince Nebuchadnezzar to allow them to exchange bread and water for the required meal due to their personal reasons. Their plea was accepted that they should have only bread and water. After only ten days it was noticed, those who have switched to bread and water appear healthier and well nourished than those who have stuck to wine and meat.

1537

Renaissance surgeon Ambroise Parè accidentally mixes a concentration of oil of rose, turpentine and egg yolk as a replacement for the regular oil medication for treating open wounds.

1600

A group of nomads heading towards East Indies through dense forests and sea routes as a part of their meal added sour oranges and lemon help them improve their health and fitness required to wander far off lands.

1747

First ever controlled clinical trial recognized was conducted by James Lind in which he succeeded in proving the medical behavior of lemon juice.

19th Century

Clinical Trials with the concept of Placebo emerge. This brings in a system of conducting clinical trials with the need of emergence of regulatory authorities.

20th Century

A shift from paper based complex clinical trials towards a simplified electronic reliable systems to count down on time and cost and there by rocketing productivity.

ClinAsia can fill in as a bridge in this transition and help its clients to bring out the miracles of medicine to the mankind…
http://www.clinasia.com/

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